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The PLA-VEGF microparticles as well as the recombinant VEGF121 were investigated for his or her bioactivity in man umbilical vein endothelial cells (HUVEC). VEGF released in vitro from PLA microparticles on times 1, 20, and 30 showed remarkable biological task compared to PBS-loaded PLA microparticles like the ability of this cells to proliferate, migrate, and type tubes similar to recombinant VEGF121. Besides, PLA-VEGF microparticles additionally the recombinant VEGF121 were also tested

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