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albicans. Consistently, the pho80/pho80 mutant mimics an artificial phosphate starvation state and mates efficiently at both lower and higher phosphate concentrations. Our study establishes a link between the PHO pathway and white-opaque epigenetic switching in C. albicans.In this paper, we investigate the effects of spin-dependent electron and defect in the carbon-based molecular device. Our proposed molecular device is designed by two carbon chains, which is bonded to a defect. The defect topology includes pentagonal and octagonal carbon rings, which is p