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Additionally, we apply the proposed method to four publicly available datasets, and the results show that our methods may be helpful for the detection and analysis of retinopathy.The Scheimpflug measurement system has broad application prospects in the fields of tomographic particle image velocimetry (PIV), ophthalmology, and three-dimensional reconstruction. Additionally, its special imaging structure makes the theoretical model of other traditional calibration methods no longer applicable. A cross-point calibration method in which