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Cox regression evaluation was made use of to model the cause-specific risk of RR developing because the first event to quantify the result of adjuvant systemic treatment and whole-breast radiotherapy (RT) on RR occurrence at 5 years. OUTCOMES the analysis included 13,512 patients. Of these patients, 162 practiced an RR. The CIF of RR at 5 many years ended up being 1.3% (95% confidence interval [CI], 1.1-1.5%), whereas the CIFs for death along with other events had been 4.4% and 9