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Questions on sustainable and appropriate cropping systems for bioenergy sweet sorghum in the smallholder farming sector still exist. Therefore, a short-term experiment was carried out to study the influence of management on microbial biomass carbon (MBC), β-glucosidase, acid phosphatase, and urease activities in a sweet sorghum cropping system in South Africa. Tillage [no-till (NT) and conventional tillage (CT)], rotation [sorghum-vetch-sorghum (S-V-S) and sorghum-fallow-sorghum (S-F-S)] and residue retention [0%, 15% and 30%] were evalu