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Treatments For ADHD in Adults The same methods that work for children help adults manage their ADHD symptoms. They include therapy, medication, and various coaching and coping techniques. Methylphenidate (MPH) is the most frequently used medication to treat adult ADHD. This class of medications works by increasing activity in specific areas of the brain that control attention and behavior. Stimulant Medication Stimulant medication is the foundation of treatment for ADHD. Numerous medications work by increasing levels of norepinephrine and dop