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Non Prescription ADHD Medication For many people with ADHD the first step in treatment is taking medication. Medication can improve focus and reduce impulsivity. The most frequently used medication for ADHD is stimulants. They function by increasing the levels of neurotransmitters dopamine and norepinephrine that are found in the brain. They come in both short-acting and longer-acting versions. 1. Stimulants Many people with ADHD take stimulant medications that increase the levels of norepinephrine and dopamine in the brain. These medications enhanc