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3% visibility). In Ukraine, as well as in Europe, the incidence and mortality of gastric cancer in men is 2 times higher than in women. Conclusions Incidence and mortality rates have declined in Europe in the past decades. Trends in the ten-year dynamics of reducing the incidence and mortality of gastric cancer in Ukraine prove the effectiveness and feasibility of introducing preventive measures at the state level in the future. Conclusions Incidence and mortality rates have declined in Europe in the past decades. Trends in the ten-year

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9% (P=0.001). Spells' frequency reduction (P=0.001) occurred within 3months with VPA. The independent prdictors for spell' frequency reduction were reduction of anger and crying [OR=4.52(95%CI=2.35-6.04), P =0.01]. VPA therapy reduces CBHS' frequency. Mood improvement is a suggestive effective mechanism. [a]www.clinicaltrials.gov[/a] identifier is NCT04482764. [a]www.clinicaltrials.gov[/a] identifier is NCT04482764.Pseudomonas aeruginosa is a gram-negative bacterium that exists in various ecosystems, causing severe infections in patients with