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This neurogenesis was associated with an increased density of fibres immunoreactive for the orexigenic neuropeptide Y (NPY). This hypothalamic plasticity observed in a migratory, but not in a non-migratory, species in response to photoperiod and food quality might represent an adaptation to the pre-migratory fattening, as required to support the extensive energy expenses that incur during the migratory flight.The gaze-cueing effect is a robust phenomenon which illustrates how attention can be shaped by social factors. In four experiments, the present study

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The increased ATP/O ratio observed in cells from old compared to adult rats was diminished after stimulation of cGMP-signaling. Opposite, long-term-PDE5-inhibition decreased cGMP-signaling and improved mitochondrial function/dynamics in Leydig cells from old rats. Mitochondrial abundance in Leydig cells decreased while ATP levels increased. Chronic-treatment elevated Tfam, Nrf1, Nrf2, Opa1, Mfn1, Drp1 and normalized Pink1 expression. Altogether, long-term-PDE5-inhibition prevented age-related NO and cGMP elevation, improved mitochondr