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We evaluated 409 participants, with 130 (31.8%) diagnosed as belonging to the CIRG. There was an association between CIRG and various parameters age ≥60years old (adjusted odds ratio [AOR], 2.70; 95% confidence interval [CI], 1.48-4.9, having a referral (AOR, 1.83; 95% CI, 1.12-3.0, diameter of LN≥2cm (AOR, 1.91; 95% CI, 1.05-3.48), fixed LNs (AOR, 2.74; 95% CI, 1.02-7.37), and lactate dehydrogenase (LD) ≥400U/L (AOR, 3.78; 95% CI, 1.46-9.77). Eighty-two percent of LD≥400 cases in the CIRG were infectious mononucleosis or necrotizing l