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nt modifies this risk or not. Patients with ischaemic stroke initiated on AD therapy are at increased risk of poor clinical outcomes and readmission even after PS adjustment, suggesting that poststroke depression requiring medication is a poor prognostic sign. Further research is needed to explore the reasons why depression is associated with worse outcome, and whether AD treatment modifies this risk or not. The risk of disability and mortality is high among recurrent stroke, which highlights the importance of secondary prevention measu

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