https://www.selleckchem.com/
RESULTS From the final qualifying studies, three did not show any statistically significant effect on gingival inflammation after probiotic administration of up to 1 month. Similarly, non-significant differences were noted in another study regarding white spot lesions development (mean administration for 17 months). No adverse effects were reported and the level of evidence was considered moderate. CONCLUSIONS Supplementation of orthodontic patients with probiotics did not affect the development of inflammation in the gingivae and decalcification in the ena