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pylori infection. The present two cases demonstrate further evidence of a new histological subtype of gastric adenocarcinoma mixed fundic and pyloric mucosa-type adenocarcinoma, which has distinct characteristic endoscopic findings. The incorporation of crossover in randomised controlled trials is accepted as an ethical obligation, especially in cancer clinical trials. The more common type of crossover is crossover allowance, which allows patients assigned to one arm to switch to another arm if there is an established benefit in the cros