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It stated that Saikosaponin A, one of many constituents from Chinese herb Bupleurum chinense, has pharmacological task in anti-depression. Thus, this research aimed to elucidate the possibility effects and components of Saikosaponin the on the depression-like behavior after cerebral ischemic damage in rats. The rat style of PSD ended up being caused by middle cerebral artery occlusion(MCAO) coupled with persistent unpredictable moderate stress(CUMS) and separation. Behavior tests including open