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Intracranial pressure (ICP) monitoring has become an important tool in neurocritical care. Despite being used in ICUs all over the world, many are unfamiliar with its origins and the people and events that shaped the development of this technique. Herein, we provide a comprehensive historical review of the evolution of ICP monitoring, beginning with the earliest descriptions of the cerebrospinal fluid. We conducted a database search in PubMed, Google Scholar, and Google Books for relevant articles using the keywords "cerebrospinal flui

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Microsporidia of the genus are generally connected with severe infections with lethal outcome in immunodeficient hosts. In immunocompetent hosts, microsporidiosis typically establishes a balanced host-parasite relationship that produces minimal clinically overt disease. Although the alimentary tract represents one of the main primary target tissues, the mechanisms of reaching other tissues during systemic microsporidian infections remain unclear. In the present study, we tested the relation between inflammation induction in immunocom