https://www.selleckchem.com/pr....oducts/epacadostat-i
Background Gorham-Stout disease (GSD) is a rare and idiopathic bone disorder, characterized by massive osteolysis. To date, there is no established treatment strategy for GSD. We empirically treated two patients, who had presented to us with cranial lesions of GSD. Here, we propose a novel algorithm for the management of Gorham's disease based on our experience and review the literature published to date.Methods We reviewed all existing literature on GSD describing the pathophysiology and suggested treatment methods, up t