https://www.selleckchem.com/peptide/avexitide.html
Alzheimer's disease is the most frequent diagnosis of neurodegenerative dementia with early (≤65 years) and late (65 years) onset ages in familial and sporadic patients. Causal mutations in 3 autosomal dominant Alzheimer genes, i.e. amyloid precursor protein (APP), presenilin 1 (PSEN1) and presenilin 2 (PSEN2), explain only 5%-10% of early-onset patients leaving the majority of patients genetically unresolved. To discover potential missing genetics, we used whole genome sequencing data of 17 early-onset patients with well-documente

https://www.selleckchem.com/products/fr180204.html
Increases in fasting plasma glucose (PG) levels lead to a decrease in 2-deoxy-2-[ F]fluoro-D-glucose ([ F]FDG) uptake in the normal brain, especially in the precuneus, resulting in an Alzheimer's disease (AD)-like uptake pattern. Therefore, patients with higher PG levels, such as those with diabetes, can be erroneously diagnosed with AD when positron emission tomography (PET) imaging is done using [ F]FDG, due to reduced uptake of [ F]FDG in the precuneus. To help avoid an erroneous diagnosis of AD due to differences in glucose metabol