https://www.selleckchem.com/pr....oducts/bms-986365.ht
Levels of inflammatory cytokines IL-1β and TNF-α in spinal cord and serum were detected by ELISA. Results Mechanical allodynia induced by PTX in both paws (right and left) of rats was significantly attenuated by EA but not sham EA treatment. In addition, EA, but not sham EA, inhibited the activation of both microglia (TMEM119) and astrocytes (GFAP) in lumbar spinal cord. Moreover, Western blot analysis revealed that protein expression of TLR4 and NF-κB in spinal cord was suppressed by EA but not sham EA treatment. PTX significantly i
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