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Institutionalized older adults have a high prevalence of frailty and disability, which may make them more vulnerable to the negative consequences of coronavirus disease 2019 (COVID-19). We investigated the impact of COVID-19 on the level of frailty, physical, and cognitive performance in nursing home residents. Nested case-control study. The study included nursing home residents who were infected with COVID-19 (case group, n=76), matched by age to a control group (n=76). Participants' sociodemographic and medical data were collected, and