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Regarding BDNF, a significant decrease (p less then 0.05) in the NW group and an increase (not statistically significant) in the NW with RSA group was found. A comparative analysis of cognitive and depression outcomes and changes in BDNF and GDNF concentration showed no significant differences in the efficacy of either form of training. Training loads resulted in a significant increase in VO2max in both the NW (p less then 0.01) and NW with RSA (p less then 0.05) groups. This indicates an improvement in cardiopulmonary efficiency of the ex
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