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To qualitatively evaluate the quality of the data collection process used by the Chinese national HIV/AIDS data repository (CRIMS), using a four-dimensional (4D) framework. The process is vital for the acquisition of high-quality data for ending the HIV/AIDS epidemic in China. The study was carried out in China from September 2014 to April 2015. Stratified convenient sampling was conducted to recruit 28 study participants including health administrators, public health professionals and clinicians. Data were collected through semi-struct