https://www.selleckchem.com/pr....oducts/Paclitaxel(Ta
COX1, COX2 and PTGES3 were significantly upregulated at the protein level in breast cancer compared to normal tissues (P 0.005). However, only PTGES3 expression was elevated at both the mRNA and protein level in breast cancer (P 0.0005). PTGES3 is the most highly expressed enzymes within the COX/PG pathway in both luminal and basal epithelial cells in normal breast tissues. Using Cox Regression Kaplan-Meier survival analysis, PTGES3 expression had a significant inverse prognostic association with breast cancer surviv