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Vaccines are one of the greatest medical innovations of all time, but there has been skepticism about them throughout history. Although initial concerns about scarcity increased public demand for COVID-19 vaccines, as supply meets demand, vaccine hesitancy may become a defining theme of the next stage of the COVID-19 pandemic. RNA vaccines against coronavirus disease 2019 (COVID-19) have demonstrated ∼95% efficacy in phase III clinical trials. Although complete vaccination consisted of 2 doses, the onset of protection for both licensed RNA vaccine

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