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nel gene mutation and acquired epilepsy. Together, these data demonstrate a novel pathophysiology for genetic epilepsy, increased neuroinflammation, which is a common mechanism for acquired epilepsy. The findings thus provide the first link of neuroinflammation between genetic epilepsy associated with an ion channel gene mutation and acquired epilepsy.This manuscript examines the structural causes of the gender gap in political interest. In many countries, men are more interested in politics than women. Yet, in others, men and women prove