https://www.selleckchem.com/pr....oducts/tenalisib-rp6
PURPOSE In contrast to the predominant chronic UV-exposure-induced cutaneous melanoma in Caucasians, acral and mucosal comprise the majority of melanomas in Asia and respond less effectively to established treatments. The clinical application of PD-1 blockade is yet to be explored in metastatic melanoma in China. EXPERIMENTAL DESIGN This phase II study was to evaluate safety and efficacy of toripalimab in advanced Chinese melanoma patients who had failed in systemic treatments. Toripalimab was given at 3 mg/kg IV Q2W until dise