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0 (5) vs 16.0 (23), P-value .001, and median treatment duration [IQR] 5.5 (11) vs 19.0 (29) weeks, P-value .007). Patients with HH reach a safe TSAT 70% significantly sooner and with less treatment procedures with TE compared to PBM. Patients with HH reach a safe TSAT less then 70% significantly sooner and with less treatment procedures with TE compared to PBM.A series of N-((4-sulfamoylphenyl)carbamothioyl)alkanamides (5a-j) were synthesized by the reaction of sulphanilamide in dry acetone with freshly prepared alkyl and acyl isot