https://www.selleckchem.com/pr....oducts/anlotinib-al3
PURPOSE To investigate the effect of early treatment of Class II division 1 malocclusion with T4K appliance on soft and hard tissue changes and prognosis of patients with mixed teeth. METHODS Twenty patients with Class II malocclusion, 11 males and 9 females, aged from 9 to 14 years, with an average age of 11.05 years, were selected. All patients were treated with T4K appliance for 12 months. The changes of soft and hard tissues before, 12 months after and 36 months after orthodontic treatment were measured and compared, to exp

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