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We detected no effects of caffeine and nonsuperiority testing ruled out medium and large enhancements in both average (1200 mg per week) and low-consumers (50 mg per week). Our results raise doubts about a caffeine-mediated enhancement of mnemonic discrimination on two counts If the effect exists, it (1) is substantially smaller than originally reported and (2) may reflect an offset of performance-impairing withdrawal symptoms rather than genuinely enhanced consolidation. We recommend that future studies employ an alternating exposure-ab