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Even thought the dose close to the acceptable daily intake does not affect those activities, a strict control of tartrazine dose in high-consumption foods especially among children is an indispensable task. © Korean Society of Toxicology 2019.Chronic alcohol consumption has been implicated in male infertility, whereas Carica papaya (CP) ripe fruit possesses antioxidant activity. This study investigated histomorphological and hormonal effects of ripened CP in alcohol experimental model. Thirty Wistar rats were divided into six groups of