https://www.selleckchem.com/pr....oducts/muvalaplin.ht
Ferroptosis is an unique iron-dependent cell death form and currently has been shown to closely relate with ER. Revealing the viscosity fluctuations of ER during ferroptosis is of great significance not only to monitor the occurrence and development of iron poisoning, but also to deeply understand the biological effects of ER in ferroptosis. Herein, we present an ER-targeting fluorescent probe (PV1) to detect viscosity changes of ER during ferroptosis. PV1 utilized a rotatable C-C bond to connect the two rigid π-systems, and responde