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https://www.selleckchem.com/pr....oducts/polyinosinic-
Introduction The main role of preservatives in eyedrops is to ensure sterility and microbiological integrity of the drug, and to facilitate the penetration of active compounds into the eye. However, several studies documented significant toxic effects induced by preservatives, especially on the ocular surface. Consequently, most of the ophthalmic medications became progressively available in preservative-free (PF) formulations. Areas covered We analyzed pre-clinical and clinical studies on PF eyedrops with p