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How a VC Can Affect Your Heart Many people experience occasional PVCs with no problems. However, if they happen frequently, PVCs can weaken your heart muscle and increase your risk of heart failure. The rhythm of your heart is usually controlled by a group of fibers located in the upper right-hand corner of your heart. This is known as the sinoatrial nerve, or SA. Electrical signals are transmitted to the lower heart chambers or ventricles. Causes PVCs are caused when the electrical impulse that normally initiates your he
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