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How a VC Can Affect Your Heart Many people have occasional PVCs with no problems. However, if they happen frequently, PVCs can weaken your heart muscle and increase your risk of heart failure. The heart's rhythm is controlled by a group of nerve fibers situated in the upper right-hand corner of your heart. This is called the sinoatrial node or SA. Electrical signals travel from this node to the lower heart chambers or ventricles. Causes PVCs occur when the electrical impulse that normally starts your heartbeat at the Sin
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