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Considering costs for retraining, the breakeven point is reached if the TIP prevents retraining in approximately 64% of participants. CONCLUSIONS The decreased COI in this long-term evaluation indicates that the TIP is cost-effective in patients with severe OSD. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.BACKGROUND Metal work apprentices (MWAs) frequently develop work-related hand eczema (HE). OBJECTIVES To evaluate the effect of health education on incidence o