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tissue. Finally, this agent should also be evaluated with animal-specific imaging devices. The continuous need for new anticancer drugs is a never-ending task due to cancer resistance to the existing drugs. This article aimed to Design, synthesis, characterization, and anticancer evaluation of cyanopyridines, pyridopyrazolopyrimidines and pyridopyrazolotriazines. FTIR spectra were recorded on Thermo nioclet iso10 FT-IR. 1H and 13C NMR spectra were recorded on on JEOL (500 MHz) and Bruker 400 MHz spectrometer. Anticancer activity was deter