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How Can Affect Your Heart PVCs are common and can be experienced by a variety of people with no cause for concern. But if they occur frequently, PVCs can weaken your heart muscle and increase your risk of heart failure. The rhythm of your heart is usually controlled by a group of fibers that are located in the upper right-hand corner of your heart. This is known as the sinoatrial nerve, or SA. Electrical signals travel from this node to the lower chambers of your heart, or ventricles. Causes PVCs happen when the electrica
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