https://www.selleckchem.com/pr....oducts/rocaglamide.h
Biodistribution in SCID mice bearing MCF7 xenografts, demonstrated excellent tumor uptake (12% ID/g) and favorable kinetics for MUC1-FA-[ F] SFB over MUC1-[ F]SFB. The tumor uptake was blocked by the excess co-injection of cold peptides suggesting the receptor-mediated process. Initial PET/CT imaging of SCID mice with MCF7 xenografts, confirmed these observations. These results demonstrate that MUC1-FA-[ F] SFB may be a useful PET imaging probe for breast cancer detection and monitoring tumor response to the treatment. Initial PET/C
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