https://www.selleckchem.com/products/pyr-41.html
Sigma 1 Receptor (Sig1R), a pluripotent modulator of cell survival, is a promising target for treatment of retinal degenerative diseases. Previously, we reported that administration of the high-affinity, high-specificity Sig1R ligand (+)-pentazocine, ((+)-PTZ) beginning at post-natal day 14 (P14) and continuing every other day improves visual acuity and delays loss of photoreceptor cells (PRCs) in the Pde6βrd10/J (rd1 mouse model of retinitis pigmentosa. Whether administration of (+)-PTZ, at time points concomitant with (P18) or follow
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