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The purpose of this work is to study the possibility of using cartridges with a mixed sorbent C8/SAX for the extraction of synthetic cannabimimetic metabolites MDMB (N)-073F from urine. It was used enzymatic hydrolysis of urine, solid phase extraction using cartridges C8/SAX and C8/SCX with mixed phase, derivatization and gas chromatography with a mass spectrometric detector. The results of the study allow us to recommend cartridges for solid-phase extraction with an anion-exchange phase (C8/SAX or SAX) when conducting a targeted study
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