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These findings provide the first direct experimental evidence for the impact of Alzheimer's disease and ischemic stroke on the Hcy metabolism of brain neurons and the associated neuron injury.Boron nitride (BN) has been widely studied as an efficient catalyst for oxidative propane dehydrogenation (OPDH). Oxygen-containing boron species (e.g., BO·, B(OH)xO3-x) are generally considered as the active centers in BN for OPDH. Here, we show an effective progressive substitution strategy toward the development of boron-oxygen-nitrogen nanotubes