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Among men, uNTX demonstrated significant negative correlation with collagen crosslinks (XLR ratio of mature to immature collagen crosslinks) in IC-C, V-T, and V-C. In addition, uNTX was positively correlated with acid phosphate substitution (HPO4, a parameter of new bone formation) in IC-C, IC-T, and V-C. After age adjustment, HPO4 in IC-T and V-C among men showed significant positive associations with uNTX (IC-T p=0.018, R 2 = 0.544; V-C p=0.007, R 2 = 0.672). We found associations between FTIR parameters and uNTX in men, but not in wo