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There was no difference in rates of extra-hepatic metastases, recurrence in the liver after resection or RAS, BRAF or p53 mutational status. After propensity weighting and Cox-regression, right-sided tumours were independently associated with significantly reduced 10year OS (HR 1.56, 95% CI 1.03-2.36, p = 0.04) but not 5year DFS (HR 1.36, 95% CI 0.89-2.08, p = 0.15). Compared with left colonic and rectal tumours, right-sided colonic tumours are independently associated with inferior OS after resection of CRLM. This is despite higher rate