https://www.selleckchem.com/pr....oducts/pf-06463922.h
Chemotherapeutic agents; cyclophosphamide (CYC) is used for treatment of cancer and autoimmune diseases. Grievously, CYC is non-selective as it affects both tumor and healthy cells resulting in systemic toxicity including placenta. The present study aimed to evaluate the effect of phosphodiesterase 5 inhibitor, sildenafil (Sild) on CYC-induced placental injury in rats. Thirty-two female Wister rats were randomly divided into 4 experimental groups. Group 1 control pregnant group; Group 2 Sild-treated pregnant rats; Group 3 pregnant r
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