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Optimal medical therapy after myocardial infarction with nonobstructive coronary arteries (MINOCA; 50% stenosis) is uncertain. We evaluated variability in discharge prescription of angiotensin-converting enzyme inhibitors / angiotensin receptor blockers (ACEI/AR and beta-blockers (B to MINOCA patients between hospitals to assess physician equipoise about secondary prevention. Patients with MINOCA between 2007-2014 were identified in the NCDR Chest Pain-MI Registry. Those with prior revascularization or missing demographic, angiogra