https://www.selleckchem.com/pr....oducts/LY315920(Vare
In this Review, we discuss the immunological aspects of COVID-19 and the potential implication of DMARDs in treating this disease. Coronaviruses can induce the production of interleukin (IL)-1β, IL-6, tumour necrosis factor, and other cytokines implicated in autoinflammatory disorders. It has been postulated that anakinra, a recombinant IL-1 receptor antagonist, might help to neutralise the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related hyperinflammatory state, which is considered to be one cause of a