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Part of HCC rats had been concomitantly addressed with 100 mg/kg salt ascorbate intraperitoneally during the 16-week duration. Hepatic areas were used for the determination of NFκB, Nrf2, TNF-α, caspase-3, caspase-8 and caspase-9.Results Sodium ascorbate significantly attenuated HCC-induced reduction when you look at the appearance of NrF2 related to a reduction in concentrations of hydrogen peroxide and superoxide anion. In addition, sodium ascorbate bl