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euronal autophagy via up-regulating the expression of Beclin-1 and LC3 Ⅱ/Ⅰ.OBJECTIVE To compare the therapeutic effect of shallow and deep needling at "Neiguan"(PC6) in the treatment of arrhythmia in rabbits. METHODS Male New Zealand rabbits were randomly divided into saline (n=15), model (n=12), shallow needling (n=13) and deep needling (n=12) groups. The arrhythmia model was established by ear intravenous injection of Barium chloride (0.4%, 1 mL/kg). Acupuncture needle was inserted into the superficial fascia (about 3 mm beneath the skin