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BACKGROUND Military personnel are required to run while carrying heavy body-borne loads, which is suggested to increase their risk of tibial stress fracture. Research has retrospectively identified biomechanical variables associated with a history of tibial stress fracture in runners, however, the effect that load carriage has on these variables remains unknown. RESEARCH QUESTION What are the effects of load carriage on running biomechanical variables associated with a history of tibial stress fracture? METHODS Twenty-one women ran at 3.