https://www.selleckchem.com/pr....oducts/17-AAG(Geldan
As the result of the intrinsic large dipole moment of thieno- and pyrrolo-pyridazines and the notably curved structure, 1 (2) has a substantial out-of-plane dipole moment of 2.0 (3.3) D in the saddle conformations. Down syndrome (DS) is associated with an increased risk of infections attributed to immune defects. Whether individuals with DS are at an increased risk of severe coronavirus disease 2019 (COVID-19) remains unclear. In a matched cohort study, we evaluated the risk of COVID-19 infection and severe COVID-19 disease