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The results of this study will be published in a peer-reviewed journal. Our meta-analysis will comprehensively evaluate the association between different digestive symptoms and the severity and mortality of patients infected with COVID-19. This study will provide evidence to help determine whether special protective measures and treatment options are needed for patients with digestive system comorbidities during the COVID-19 pandemic. INPLASY202090055. INPLASY202090055. Facial spasm causes a lot of troubles to patients daily life and ser